It just doesn’t get more charming than Charleston, South Carolina. And the best place to set up home base is hands down the Grand Bohemian Charleston. Part of the esteemed Kessler Collection, the art-driven boutique hotel has been a favorite of both locals and travelers since its debut back in 2015. It’s ideally situated in the Historic District, within walking distance of prime landmarks, shopping and dining. Guests will enjoy the artwork tucked around literally every corner, the carefully curated gallery and of course the bold, luxe accommodations. The standout offering? The wine-blending experience, which lets participants create their own unique vino while taste testing varietals and learning from the affable, knowledgeable sommelier. But consider yourself warned: When it comes time to check out, you likely won’t want to leave.